- What is MANC?
Clinoptilolite is a naturally occurring volcanic mineral with a unique crystalline structure, and is a type of zeolite. There are many different types of zeolite; however, clinoptilolite has the most research conducted on it for medicinal use in the body. Both scientific research and empirical evidence show that clinoptilolite has a unique ability to safely bind and remove toxins from the body. MANC differs from other types of clinoptilolite, because it has undertaken an advanced, double-patented purification (modifying) and activation process. This ensures the cleanest, most pure clinoptilolite, resulting in the highest functional capacity to bind toxins.
- How is MANC beneficial?
MANC works as a mineral-based gastrointestinal detoxifier by effectively binding toxins, such as heavy metals and excess endogenous waste products in the intestinal tract. MANC also strengthens the intestinal wall barrier by effectively removing toxins and intestinal irritants from the intestinal tract. Toxins and excess waste products in the intestine, such as histamine, may trigger immune system chemicals, including cytokines, which cause disruption to the intestinal barrier.
- How does it work?
MANC’s porous crystalline structure contains ‘macro-pores’ or channels creating a huge surface area. These channels attract and bind heavy metals, toxins, and other excess metabolites, such as histamine and ammonium. It naturally possesses an electrical charge that acts like a magnet, powerfully drawing toxins into the crystalline structure, capturing and binding them permanently. MANC is not absorbed through the intestinal tract and passes safely out through the colon carrying with it all the bound impurities; thereby, reducing the toxin burden of the body.
- Which toxins does MANC bind?
Research suggests MANC has a strong affinity to bind heavy metals such as mercury, lead, cadmium, arsenic, caesium and aluminum in the gastrointestinal tract. In addition, evidence shows MANC effectively binds to excess endogenous waste products, such as histamine and ammonia in the intestinal tract. Emerging research also suggests MANC may bind to environmental chemicals, pollutants and even microbial components, easing the toxin burden on the body.
- Does MANC remove beneficial minerals such as calcium, magnesium and zinc?
MANC does not remove beneficial minerals from the body. MANC possesses unique mineral properties that binds and removes heavy metals in a naturally hierarchical manner depending on their electrical charge and molecular weight. Unlike other harsh chelators, MANC prioritises the binding of mercury, lead, cadmium, arsenic and other toxins, with little or no effect on beneficial minerals. Clinical data* obtained from in vivo studies shows that the intake of MANC over a long period of time (60 months) or using higher doses, does not have a negative influence on the status of nutrient minerals, such as zinc, calcium, potassium and magnesium. *(Report on Influence of CLINOPTILOLITE and MANC on the natural balance of micronutrients.)
- How long can MANC be used?
MANC is designed for daily use and can safely be taken continuously under the care of a healthcare professional. In cases of high toxin load in the intestinal tract (for example, during the detoxification of heavy metals), 2-4 months of use is recommended. Once improved, a month’s course 3-4 times a year will assist in reducing the overall ongoing toxic load that accumulates as a result of a western lifestyle.
- Can MANC be used for ‘sensitive’ detoxifiers?
Yes. MANC has an excellent safety profile. It is rare to experience detoxification symptoms due to MANC. When people experience detoxification side-effects, it is often due to the increased mobilisation of toxins combined with insufficient elimination of toxins from the intestinal tract, leading to toxin reabsorption. MANC effectively binds toxins in the intestinal tract and ensures their safe removal from the body. It has been suggested that highly sensitive people initially begin using MANC at a lower dose, gradually building up to the recommended dose. If detoxification symptoms are experienced while taking MANC, this may also indicate that the MANC has reached its toxin saturation limit. In this case, it may be beneficial to increase the dose to provide additional binding and removal of toxins from the gastrointestinal tract.
- Is MANC safe during pregnancy?
While there is no human safety data on the use of MANC during pregnancy, various animal studies have shown that there is no adverse effect when MANC is used during pregnancy and lactation. MANC is not absorbed through the gastrointestinal tract, making it generally very safe to use.
The Gut is greatest site of toxins absorption and reabsorption
The intestinal wall villi and microvilli have a very large surface area (over 400m2), which makes the intestines the body’s greatest site of toxin absorption and reabsorption (also called enterohepatic recirculation). When toxins are metabolised by liver cells, they are packaged up (conjugated) and mixed with bile before entering the duodenum. 95% of our toxin-containing bile is reabsorbed through the large intestine, leading to the reabsorption of unwanted toxins.
In addition, dysbiotic microbiota in the intestines often produce high levels of enzymes that break-apart conjugated toxins that have been conjugated by the liver, before they are eliminated from the intestines. Enzymes such as beta-glucoronidase, sulfatase and various glycosidases ‘un-package’ conjugated toxins. This causes toxins to be rapidly reabsorbed into circulation and increases the liver’s burden, until our toxic load overwhelms the body’s detoxification capacity, causing health issues.
MANC has the unique ability to bind toxins in the intestinal tract ensuring they are effectively removed from the body, though stool elimination
MANC safely binds & REMOVES TOXINS from the intestinal tract, preventing absorption of:
There is no safe level for heavy metals in humans. Accumulation in fat cells, bones, glands, brain, or the central nervous system results in detrimental health effects, and heavy metals may also block nutrient and mineral absorption. Heavy metals are attracted and bound to MANC and carried safely out of the body, consequently reducing damage to nervous system and organs of the body. Heavy metals such as lead, mercury, cadmium & arsenic
Histamine If histamine levels exceed an individual’s tolerance, histamine-modulated symptoms will be triggered wherever histamine receptors are present (eg. skin, heart, lungs, brain and GIT) inducing allergy and inflammation. Excessive histamine levels may result from damage to enterocytes due to intestinal dysbiosis, or from a diamine oxidase deficiency (the enzyme which breaks down amines). Histamine intolerance may also be induced by medications and alcohol and also histamine excess in the diet (for example red wine, coffee, cured meats, cheeses, chocolate, seafood). Symptoms may include rashes, hives or skin irritations, migraines & headaches, circulatory problems, runny nose or nasal congestion, itchy eyes, cramping, diarrhoea, ruddy or flushed complexion. MANC effectively binds excess histamine in the intestinal tract preventing symptoms.
Ammonia & other harmful amines All amines are derived from ammonia which is a common degradation product from the metabolic breakdown of protein with large amounts also produced by microflora in our intestines. When excessive ammonia is absorbed into the body from the intestinal tract, it may burden the liver and has been linked with cognitive degeneration. Other amines such as dimethylamine and nitrosamines are be potent toxins and carcinogens. MANC is very effective at binding ammonia and other amine derivatives in the intestine; thereby, reducing the liver’s burden and protecting cognitive function. Excessive ammonia may be caused by damage or toxic burden to the liver and kidneys, genome mutations, GIT dysbiosis and diets too high in protein. Symptoms may include fatigue, foggy memory, muscle weakness, elevated uric acid and conditions affected may include gout, chronic fatigue, fibromyalgia, neurodegeneration and all conditions affecting the liver and kidneys.
POPs (persistent organic pollutants) Pollutants such as pesticides and plastics are toxins that are known to build up in our bodies and are well documented to have adverse effects, particularly endocrine system functioning. MANC is effective at removing these toxins in the intestines, preventing their absorption and reabsorption (via enterohepatic recycling).
There is some evidence (primarily in-vitro and animal studies) to suggest that MANC may have the ability to bind and remove small viral components, bacteria and mycotoxins and therefore relieve the immune system burden. Further research in this area looks promising.
Information from BioPractica